The Cast of Losing Isaiah: Where Are They Now

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  • Jessica Lange
  • Halle Berry
  • Marc John Jefferies
  • Samuel L. Jackson
  • Cuba Gooding Jr.
  • David Strathairn
  • Regina Taylor
  •  LaTanya Richardson
  • Stephen Gyllenhaal
  • Losing Isaiah

Marc John Jefferies

Then child actor Marc John Jefferies landed the role of Isaiah as a toddler. After his film debiut,  Jefferies became best known as the highly intelligent kid in the PeoplePC commerials. Since then, he's built a notewothy big screen career, starring in the cult classic B.I.G. biopic Notorious as well as hit cable series Treme. It is rumored that he's going to play Ice Cube in the film Straight Outta Compton

(Photo: Derrick Salters/

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