Pharrell, Pitbull and Shakira also among those scheduled to take the stage for the inaugural event.
The two threw slight jabs at each other last year, and Drizzy is in the midst of some Jay-baiting, so hip hop heads will have their ears perked for sure.
In between the sets, awards will be handed out in such categories as Best Collaboration, Best Lyrics, and Song of the Year. (Drake is up for his "Hold On We're Going Home" featuring Majid Jordan.) The winners will be determined by the listening audience. Fans can cast their votes now via Twitter, Facebook or the dedicated site, iheartradio.com/awards.
Get ready for the BET Experience, featuring Mary J. Blige, Maxwell, Jill Scott, A$AP Rocky, Rick Ross and many more. Click here for more details and info on how to purchase tickets.
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(Photos from left: Gaelle Beri/Redferns via Getty Images, Dave Kotinsky/Getty Images)