Nas, who is coming off a worldwide tour celebrating the 20th anniversary of his seminal debut Illmatic, and Diddy, who recently launched his own cable network, will take a moment from their whirlwind lives to play a set at the benefit, known simply as the Black Ball.
Since 2004, the "black tie fly" event has brought in $22.6 million in funds to support children and families living with HIV/AIDS in Africa and India. Last year's ball, featuring performances from Pharrell and Carole King, raised some $4 million, reports the Associated Press.
This year's event, the 11th annual Black Ball, is scheduled for Oct. 30 at the Hammerstein Ballroom and, in addition to the star power, features a live auction.
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(Photos from left: David Becker/Getty Images for Clear Channel, Dimitrios Kambouris/Getty Images, Imeh Akpanudosen/Getty Images for The Weinstein Company)