"I thank all of my fans, friends and supporters who bought tickets and hope to see you all soon," Franklin said in a statement. "I extend my sincerest regrets."
Franklin previously battled health issues that forced the cancellation of performances last year and in 2013, but she's been hitting more stages this year.
The soul legend recently traveled via tour bus from Detroit to the West Coast for three shows in California. On Monday, Franklin performed in Oakland, which was her first concert in the Bay Area in nearly four decades.
Refunds for Franklin's Sin City concert are available.
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