The suspect rammed his car into a group of pedestrians before using a large butcher knife to attack others, OSU officials said.
"Victim injuries include stab wounds, injury by motor vehicle and other injuries that are being evaluated," OSU said.
Authorities have not yet publicly released the name of the attacker.
The "Run, Hide, Fight," instruction is standard protocol for active shooter scenarios. Run means evacuate if possible; Hide means to take shelter and get out of view of a shooter; and Fight should be used as the last resort to take down a shooter in order to save yourself or others.
According to ABC News, eight people were transported to local hospitals, said a spokeswoman for the Columbus Fire Department.
At least one person has been listed in critical condition, although the fire department has not specified if anyone transported was shot.
Warning: The below image is graphic.
This story will be update as more information becomes available.
(Photo: AP Photo/Andrew Welsh-Huggins)