Deion Sanders, headead coach of the University of Colorado, has not been in attendance at the team’s football camp and out of the public eye since the 2025 NFL Draft due to an “unspecified health issue”, according to USA Today.

Sanders canceled his speaking engagement scheduled for June 8 in Florida at the Sickle Cell Disease Research and Educational Symposium. 

"Due to an unavoidable last-minute scheduling change, our originally scheduled Foundation Keynote Speaker, Deion Sanders 'Coach Prime, is unable to attend,” the organization posted on X (formerly Twitter). “We are grateful for his support and look forward to future opportunities to welcome him.”

During an appearance on Asante Samuel’s Say What Needs to be Said podcast in late May, Sanders shared that he was experiencing some physical challenges.

"I've done no media. I've done nothing for a minute. So, coming on with you is something,” Sanders explained. “ I ain't been in front of nobody for a minute. I lost about 14 pounds. I'm coming back, but I needed this.”

During a YouTube livestream, Deion Sanders Jr. said his father was resting at their home in Canyon, Texas, and is “feeling well.” “He’ll tell y’all soon enough what he's going through, what he went through,” he said in the video.

In his update, he did not reveal a timetable for his father’s return to university.

“When we get back in Boulder, I don’t know,” Deion Jr. said on June 8. “I’m waiting until my dad leaves. When he leaves, then I’ll go. Until then, I’m gonna sit here with him.”

Over the past several years, Sanders has struggled with various health issues. In June 2023, Sanders underwent emergency surgery to treat persistent blood clots in his legs. He also had two toes amputated as a result of similar blood clot issues while head coach at Jackson State University. 

Colorado opens the season at home Aug. 29 against Georgia Tech.